Utility of cooling patches to prevent hand-foot syndrome caused by pegylated liposomal doxorubicin in breast cancer patients

Table 6 Comparison of the Hand-Foot Skin Reaction and Quality of Life Questionnaire score between the two groups

HF-QOL score	1st	2nd	3rd	4th
Control group	39.14 ± 10.29	21.80 ± 10.10	18.02 ± 5.96	18.08 ± 7.01
Cooling group	39.06 ± 8.56	16.65 ± 10.46	14.22 ± 6.01	14.20 ± 7.39
F	4.559	0.061	0.192	0.025
P value	0.966	0.013	0.002	0.008

HF-QOL: Hand-Foot Skin Reaction and Quality of Life Questionnaire.