Risk factors for occult metastasis detected by inflammation-based prognostic scores and tumor markers in biliary tract cancer

Table 2 Comparison of laboratory findings and inflammation-based prognostic scores

	Type of operations
Variables	EL (n = 26)	R (n = 210)	P value
Hb (g/dL)1	12.0 ± 0.33	12.3 ± 0.11	0.78
Plt (10000/μL)1	24.4 ± 1.53	22.1 ± 0.54	0.079
PT-INR1	0.97 ± 0.03	0.99 ± 0.01	0.72
Albumin (mg/dL)1	3.73 ± 0.11	3.79 ± 0.04	0.66
ALP (IU/L)1	641 ± 98	564 ± 34	0.22
γ-GTP (IU/L)1	223 ± 51	192 ± 17	0.28
T-bil (mg/dL)1	1.74 ± 0.34	1.24 ± 0.11	0.083
LDH (IU/L)1	212 ± 16	187 ± 5.6	0.079
CRP (mg/dL)1	0.88 ± 0.93	1.23 ± 0.33	0.63
Creatinine clearance (mL/min)1	212 ± 16	187 ± 5.6	0.079
Tumor markers
CA19-9 (IU/mL)1	5198 ± 2767	777 ± 357	0.014
CEA (ng/mL)1	12.3 ± 3.1	5.1 ± 1.0	0.0054
Inflammation-based prognostic scores
NLR1	3.92 ± 0.40	2.81 ± 0.14	0.0018
PLR1	190 ± 18	166 ± 6.4	0.15
PNI1	43.4 ± 3.4	46.7 ± 1.2	0.82
mGPS (A / B, C, D)	9 / 17	126 / 84	0.012

¹Data are presented as the mean ± SD. CA19-9: Carbohydrate antigen 19-9; CEA: Carcinoembryonic antigen; NLR: Neutrophil-lymphocyte ratio; PLR: Platelet-lymphocyte ratio; PNI: Prognostic nutrition index; mGPS: Modified Glasgow prognostic score; EL: Exploratory laparotomy; R: Resected.