Gut-liver axis in cirrhosis: Are hemodynamic changes a missing link?

Table 2 Correlation matrix of links of the gut-liver axis in cirrhosis (data from human studies)

	Gut dysbiosis	Small intestinal bacterial overgrowth	Intestinal barrier dysfunction	Bacterial translocation	Systemic inflammation	Hyperdynamic circulation	Severity of cirrhosis	Complications of cirrhosis	Prognosis
Gut dysbiosis		NR	+	+	+	NR	+	+	+
Small intestinal bacterial overgrowth	NR		NR	+	+	+	+	+	NR
Intestinal barrier dysfunction	+	NR		+	+	NR	+	+	+
Bacterial translocation	+	+	+		+	+	+	+	+
Systemic inflammation	+	+	+	+		+	+	+	+
Hyperdynamic circulation	NR	+	NR	+	+		+	+	+
Severity of cirrhosis	+	+	+	+	+	+		+	+
Complications of cirrhosis	+	+	+	+	+	+	+		+
Prognosis	+	NR	+	+	+	+	+	+

+: Relations are reported; NR: Not reported.