Skeletal muscle metastasis with bone metaplasia from colon cancer: A case report and review of the literature

Figure 2 Pathology and immunohistochemistry of the primary lesion and thigh mass. A: In the resected specimen, the orange arrow points to the tumor location and the white arrow points to the appendix; B: Skeletal muscle metastasis (white arrow) on color ultrasound; C: Hematoxylin-eosin staining of the resected colon cancer specimen (magnification, 40 times); D: H&E staining of an SMM biopsy. The red dashed circle is the bone metaplasia region (magnification, 40 times); E: Part of the enlarged Figure 1D (magnification, 200 times); F: Cytokeratin staining of an SMM biopsy. The orange arrow refers to the fibroblasts in the tumor stroma and the white arrow refers to the metastatic tumor cells (magnification, 200 times).