Hemophagocytic lymphohistiocytosis secondary to composite lymphoma: Two case reports

Figure 3 Morphology of bone marrow aspirate smear and biopsy in Case 2. A and B: Hemophagocytosis (A) and tumor cells (B) (Wright’s stain, × 1000); C: Diffuse medium-sized atypical lymphocytes infiltrated with the effacement of normal architecture (hematoxylin-eosin stain, × 400); D: The tumor cells were positive for PAX-5 (immunohistochemistry, IHC × 400); E: Lymph node biopsy sections showed that nodular tissue architecture was effaced by small- to intermediate-sized lymphocytes (hematoxylin-eosin stain, × 400); F-H: The tumor cells in lymph nodes were positive for CD3 (F), TIA-1 (G) and granzyme B (H) (IHC × 400).