Prognostic implications of ferroptosis-associated gene signature in colon adenocarcinoma

Figure 4 Prognostic analysis of the five ferroptosis-related gene models in the Cancer Genome Atlas-colon adenocarcinoma cohort. A: Distribution and median value of the risk scores in the Cancer Genome Atlas-colon adenocarcinoma (TCGA-COAD) cohort. The black dotted line is the optimum cut-off dividing patients into high-risk and low-risk groups. The red curve represents high risk, and the blue curve represents low risk; B: Kaplan-Meier survival curves for the overall survival of patients in the high-risk group and low-risk group in the TCGA-COAD cohort; C: Principal component analysis plot of the TCGA-COAD cohort; D: t-distributed stochastic neighbor embedding analysis of the TCGA-COAD cohort; E: Distributions of overall survival status, overall survival, and risk score in the TCGA-COAD cohort. The red dot indicates patient death, and the blue dot indicates patient survival; F: Area under the curve values of time-dependent receiver operating characteristic curves verified the prognostic performance of the risk score in the TCGA-COAD cohort. PC: Principal component analysis; t-SNE: t-distributed stochastic neighbor embedding; AUC: Area under the curve.