Early acute fat embolism syndrome caused by femoral fracture: A case report

Table 2 Demographic profile of the reported fat embolism syndrome patients whose latent period was < 12 h

Ref.	Age/gender	Latent period	Trauma	Outcome
Tsuru and Adachi[13]	83/F	55 min	Left distal femur fracture	Comatose and eventually died
Chen et al[17]	31/M	1 h	Right femoral and tibia fracture	Comatose and eventually died
Scarpino et al[18]	17/M	2 h	Right open femur and tibia fracture	Brain death on hospital day 2
Our case	29/F	2.5 h	The middle and left femur fracture	After 29 d in a coma, she became conscious. Returned to work at 6 mo after trauma
You et al[19]	54/M	2 h 53 min	Multiple fracture (rib, clavicle, femur) and pulmonary contusion and pneumothorax	Brain death on hospital day 5
Dillerud[20]	25/M	3 h	Right femur and left tibiofibular fracture	Minimal memory impairment
Millen et al[21]	17/F	4 h	Multiple fracture (rib, clavicle, femur, tibia, fibular, pubic rami, sacral ala)	After 2 mo in a coma, she was alert, oriented, following with progressively improving cognition
Xu et al[22]	63/W	4 h	Right tibia and fibula fractures	One month later, the patient was discharged from the hospital without any residual neurological deficit
Yang et al[23]	46/W	5 h	Left femur fracture	Patient consciousness was restored but language disorders were left
Cronin et al[24]	26/M	6 h	Right open tibiofibular shaft fracture	Returned to work at 3 mo after trauma
Paredes et al[4]	54/M	10 h	Multiple fractures: Femoral shaft, radius, patella, metatarsal	A residual mild cognitive impairment