Dopamine agonist responsive burning mouth syndrome: Report of eight cases

Table 1 Clinical data of eight patients with dopamine agonist responsive burning mouth syndrome

Patient	Sex	Age (yr)	Duration of BMS (mo)	Involved sites	Clinical manifestation	VAS score	Concurrent RLS	Family history of BMS or RLS	Maintenance dose of pramipexole	Time required to achieve significant effect
1	F	53	24	Anterior 2/3 of the tongue, hard palate, lip	Oral burning pain, ant walking sensation, dry mouth symptom	6	Y	N	0.25 mg/d	2 wk
2	F	58	30	Anterior 2/3 of the tongue, hard palate, buccal mucosa	Oral burning pain, numbness, dry mouth symptom	8	Y	N	0.375 mg/d	4 wk
3	M	49	12	Anterior 2/3 of the tongue, hard palate, lip	Oral burning pain, dry mouth symptom	7	N	One brother with RLS	0.25 mg/d	4 wk
4	M	65	36	Anterior 2/3 of the tongue, hard palate, soft palate, buccal mucosa	Oral burning pain, ant walking sensation, dry mouth symptom, taste disturbance	8	N	N	0.5 mg/d	5 wk
5	F	62	42	Anterior 2/3 of the tongue, hard palate, soft palate, lip, buccal mucosa, larynx	Oral burning pain, numbness, dry mouth symptom	10	Y	One brother with RLS	0.5 mg/d	8 wk
6	M	46	24	Anterior 2/3 of the tongue, hard palate, lip	Oral burning pain, numbness	7	N	One sister with BMS	0.25 mg/d	4 wk
7	F	55	30	Anterior 2/3 of the tongue, hard palate, soft palate,buccal mucosa	Oral burning pain, dry mouth symptom	9	N	N	0.375 mg/d	6 wk
8	F	57	12	Anterior 2/3 of the tongue, lip, buccal mucosa	Oral burning pain, numbness, dry mouth symptom	7	Y	N	0.25 mg/d	3 wk

BMS: Burning mouth syndrome; RLS: Restless legs syndrome; VAS: Visual analog scale; F: Female; M: Male; Y: Yes; N: No.