Development and validation of a prognostic nomogram for colorectal cancer after surgery

Table 1 Demographic and clinicopathological characteristics of patients with colorectal cancer between 2010 and 2015 in the Surveillance, Epidemiology, and End Results database

Demographic or characteristic	All subjects (n = 3139)	Training set (n = 2902)	Validation set (n = 1047)	P value
Sex				0.0239a
Male	1560	1070	490
Female	1579	1022	557
Age at diagnosis, yr				0.7318
20-55	853	570	283
55-65	722	469	253
65-75	736	497	239
> 75	828	556	272
Race				0.7521
Black	378	254	124
White	2445	1622	823
Other (American Indian/Alaska Native, Asian/Pacific Islander)	316	216	100
T stage				0.0141a
Tis	36	27	9
T1	458	306	152
T2	499	329	170
T3	1522	1101	421
T4	624	419	205
N stage				0.3186
N0	1633	1084	549
N1	876	573	303
N2	630	435	195
M stage				0.7900
M0	2713	1811	902
M1	426	281	145
Serum CEA level				0.7262
Normal	1838	1230	608
Elevated	1301	862	439
Tumor deposit				0.9484
Negative	2698	1797	901
Positive	441	295	146
Grade				0.6182
I	279	185	94
II	2096	1405	691
III	573	383	190
IV	191	119	72
Tumor size				0.0809
≤ 30 mm	876	597	279
30-50 mm	934	642	292
50-65 mm	555	351	204
> 65 mm	774	502	272
LNR, mean (range)	0.1173 (0-1)	0.1197 (0-1)	0.1124 (0-1)	0.3699
LODDS, mean (range)	-1.6777 (-3.2555-2.9827)	-1.6683 (-3.2555-2.9827)	-1.6964 (-3.2555-2.8457)	0.5083
PLN, mean (range)	2.2698 (0-48)	2.3384 (0-48)	2.1328 (0-48)	0.2387
RLN, mean (range)	20.7330 (1-90)	20.6415 (1-90)	20.9160 (1-90)	0.4843

^aP < 0.05.

LNR: Lymph node ratio; LODDS: Log odds of positive lymph nodes; PLN: Positive lymph node; RLN: Resected lymph node.