Observational Study
Copyright ©The Author(s) 2021.
World J Clin Cases. Jun 26, 2021; 9(18): 4668-4680
Published online Jun 26, 2021. doi: 10.12998/wjcc.v9.i18.4668
Table 2 Univariate and multivariate analyses for predictors of disease-free survival
Factor
Univariable analysis

Multivariate analysis



AWGS2019

EWGSOP2

HR (95%CI)
P value
HR (95%CI)
P value
HR (95%CI)
P value
AWGS20193.311 (2.470-4.439)0.001b2.150 (1.547-2.988)0.001b
EWGSOP22.566 (1.803-3.651)0.001b1.599 (1.092-2.339)0.016a
Age1.036 (1.021-1.051)0.001b
Gender
Male/female1.038 (0.745-1.448)0.824
BMI0.934 (0.890-0.980)0.005b
Albumin0.930 (0.904-0.957)0.001b
Hypertension
Yes/No1.290 (0.948-1.755)0.105
Diabetes
Yes/No0.765 (0.476-1.229)0.268
ASA grade
II/I1.301 (0.773-2.190)0.323
III/I2.402 (1.366-4.225)0.002b
CCI1.288 (1.146-1.448)0.001b
Operative duration1.003 (1.001-1.006)0.017a
TNM stage
II/I2.494 (1.349-4.610)0.004b1.660 (0.887-3.108)0.1131.636 (0.872-3.067)0.125
III/I8.093 (4.825-13.574)0.001b4.751 (2.753-8.200)0.001b4.968 (2.876-8.582)0.001b
Laparoscopic surgery
Yes/No0.463 (0.306-0.700)0.001b
Type of resection
Total/Subtotal1.864 (1.400-2.481)0.001b
Anastomosis method
B2/B12.571 (1.672-3.954)0.001b1.414 (0.904-2.210)0.1291.423 (0.911-2.223)0.122
RouY/B12.747 (1.920-3.390)0.001b1.614 (1.109-2.348)0.012a1.600 (1.100-2.328)0.014a
Lymph node dissection
D2/D11.036 (0.693-1.548)0.864
Histologic type
Undifferentiated/differentiated2.756 (1.855-4.095)0.001b1.899 (1.263-2.856)0.002b1.972 (1.309-2.970)0.001b
Total complications1.678 (1.221-2.307)0.001b
Pneumonia2.574 (1.601-4.137)0.001b1.990 (1.222-3.241)0.006b1.935 (1.184-3.163)0.008b
Leakage3.325 (1.757-6.292)0.001b3.018 (1.557-5.853)0.001b3.339 (1.722-6.476)0.001b
Wound infection1.171 (0.435-3.153)0.755
Intestinal obstruction2.159 (0.888-5.252)0.090
Gastrointestinal dysfunction0.982 (0.484-1.994)0.960
Intra-abdominal infection1.410 (0.767-2.594)0.269
Intra-abdominal hemorrhage0.888 (0.365-2.160)0.794
Venous thrombosis0.997 (0.410-2.425)0.995
First time to Flatus1.101 (1.050-1.154)0.001b
Hospital stay1.026 (1.017-1.035)0.001b
Readmission within 30 d1.601 (0.929-2.759)0.090