Copyright
©The Author(s) 2021.
World J Clin Cases. Apr 16, 2021; 9(11): 2458-2468
Published online Apr 16, 2021. doi: 10.12998/wjcc.v9.i11.2458
Published online Apr 16, 2021. doi: 10.12998/wjcc.v9.i11.2458
Table 2 Relationship between expression of mismatch repair protein and clinicopathological characteristics in elderly colorectal cancer patients
Clinical pathology data | n | MMR | χ2 | P value | |
dMMR | pMMR | ||||
Gender | 0.005 | 0.945 | |||
Male | 196 | 19 | 177 | ||
Female | 131 | 13 | 118 | ||
Tumor size | 3.907 | 0.048 | |||
≥ 5 cm | 112 | 16 | 96 | ||
< 5 cm | 215 | 16 | 199 | ||
Pathological type | 0.456 | 0.796 | |||
Adenocarcinoma | 281 | 27 | 254 | ||
Mucinous adenocarcinoma | 43 | 5 | 38 | ||
Other | 3 | 0 | 3 | ||
Tumor morphology | 1.768 | 0.622 | |||
Ulcer type | 181 | 19 | 162 | ||
Raised type | 77 | 9 | 68 | ||
Ulcer raised type | 45 | 3 | 42 | ||
Other | 24 | 1 | 23 | ||
Tumor site | 32.368 | 0.000 | |||
Right colon | 78 | 19 | 59 | ||
Left colon | 90 | 11 | 79 | ||
Rectum | 159 | 2 | 157 | ||
Differentiation | 8.181 | 0.085 | |||
High | 4 | 1 | 3 | ||
High-moderate | 15 | 1 | 14 | ||
Moderate | 241 | 18 | 223 | ||
Moderate-poor | 59 | 10 | 49 | ||
Poor | 8 | 2 | 6 | ||
Lymph node metastasis | 2.003 | 0.157 | |||
Yes | 130 | 9 | 121 | ||
No | 197 | 23 | 174 |
- Citation: Fan JZ, Wang GF, Cheng XB, Dong ZH, Chen X, Deng YJ, Song X. Relationship between mismatch repair protein, RAS, BRAF, PIK3CA gene expression and clinicopathological characteristics in elderly colorectal cancer patients. World J Clin Cases 2021; 9(11): 2458-2468
- URL: https://www.wjgnet.com/2307-8960/full/v9/i11/2458.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v9.i11.2458