Prognosis factors of advanced gastric cancer according to sex and age

Table 4 Multivariate analysis of factors influencing survival according to age using a Cox proportional hazards model

Characteristic	≤ 60 yr old			> 60 yr old
	P value	HR	95%CI	P value	HR	95%CI
Sex
Male		1.000			1.000
Female	0.300	1.116	0.907-1.373	0.017	0.780	0.636-0.957
Tumour size
≤ 5 cm		1.000			1.000
> 5 cm	0.001	1.973	1.586-2.454	0.086	1.187	0.976-1.444
Lymphovascular invasion
No		1.000			1.000
Yes	0.001	1.783	1.441-2.206	0.001	1.580	1.307-1.910
Lymph node metastasis
No		1.000			1.000
Yes	0.485	0.929	0.756-1.142	0.147	0.872	0.725-1.049
Depth of invasion
Muscularis propria	0.185	0.570	0.249-1.308	0.371	0.746	0.392-1.418
Sub-serosal	0.280	0.638	0.283-1.441	0.472	0.792	0.420-1.495
Serosal exposed	0.214	0.594	0.262-1.350	0.465	0.786	0.412-1.500
Serosal invasion	0.518	0.724	0.272-1.929	0.549	0.765	0.318-1.839
Histology
Tubular adenocarcinoma (well)		1.000			1.000
Tubular adenocarcinoma (moderate)	0.731	0.891	0.463-1.718	0.010	2.547	1.246-5.205
Tubular adenocarcinoma (poorly)	0.929	0.972	0.514-1.837	0.004	2.812	1.380-5.730
Signet ring cell carcinoma	0.427	1.309	0.674-2.543	0.001	3.652	1.700-7.843
Mucinous adenocarcinoma	0.134	0.525	0.226-1.220	0.002	3.847	1.648-8.979

HR: Hazard ratio; CI: Confidence interval.