Retrospective Study
Copyright ©The Author(s) 2020.
World J Clin Cases. Nov 6, 2020; 8(21): 5188-5202
Published online Nov 6, 2020. doi: 10.12998/wjcc.v8.i21.5188
Table 1 Clinical characteristics 56 patients of coronavirus disease 2019
Clinical characteristics, symptoms or signs

Disease severity
Composite endpoint

All patients, n = 56
Non-severe, n = 45
Severe, n = 11
P value
Yes, n = 5
No, n = 51
P value
Age, median (range), yr45.0 (21.0-80.0)45.4 (21.0-80.0)46.1 (26.0-70.0)0.68943.8 (26.0-70.0)45.6 (21.0-80.0)0.601
Age groups, n (%)
0-14 yr0/56 (0.0)0/45 (0.0)0/11 (0.0)0.7800/5 (0.0)0/51 (0.0)0.280
15-49 yr35/56 (21.0-49.0)29/45 (21.0-49.0)6/11 (26.0-45.0)-4/5 (26.0-45.0)31/51 (21.0-49.0)-
50-64 yr15/56 (50.0-64.0)11/45 (50.0-64.0)4/11 (50.0-57.0)-0/5 (0.0)15/51 (50.0-64.0)-
≥ 65 yr6/56 (66.0-80.0)5/45 (66.0-80.0)1/11 (70.0)-1/5 (70.0)5/51 (66.0-80.0)-
Female sex, n (%)32/56 (57.1)24/45 (53.3)8/11 (72.7)0.3193/5 (60.0)29/51 (56.9)1.000
Smoking history, n (%)
Never smokers45/56 (80.3)38/45 (84.4)7/11 (63.6)0.1704/5 (80.0)41/51 (80.3)0.450
Long-term smoking6/56 (10.7)4/45 (8.9)2/11 (18.2)-0/5 (0.0)6/51 (11.8)-
Occasionally smoking5/56 (8.9)3/45 (6.7)2/11 (18.2)-1/5 (20.0)4/51 (7.8)-
Exposure to source of transmission within 14 d, n (%)
Local residents of Wuhan6/56 (10.7)4/45 (8.9)2/11 (18.2)0.1292/5 (40.0)4/51 (7.8)0.125
Wuhan short-term tourism history17/56 (30.4)12/45 (26.7)5/11 (45.4)0.2801/5 (20.0)16/51 (31.4)1.000
NCP patient exposure history27/56 (48.2)24/45 (51.1)3/11 (27.3)0.1811/5 (20.0)26/51 (50.9)0.353
Contacted NCP patients and confirmed diagnosis5/56 (8.9)4/45 (8.9)1/11 (9.1)1.0001/5 (20.0)4/51 (7.8)0.385
No explicit exposure history1/56 (1.8)1/45 (2.2)0/11 (0.0)1.0000/5 (0.0)1/51 (1.9)1.000
Symptoms or signs, n (%)
Fever42/56 (75.0)31/45 (68.9)11/11 (100.0)0.0495/5 (100.0)37/51 (72.5)0.316
Temperature on admission, °C37.4 (36.1-39.8)37.3 (36.1-39.8)38.3 (36.7-39.7)-38.3 (37.7-38.9)37.0 (36.1-39.8)-
< 37.522/56 (39.3)21/45 (46.7)1/11 (9.1)0.0000/5 (0.0)29/51 (56.8)0.007
37.5-38.022/56 (39.3)21/45 (46.7)1/11 (9.1)-1/5 (20.0)13/51 (25.5)-
38.1-39.010/56 (17.8)2/45 (4.4)8/11 (72.7)-4/5 (80.0)8/51 (15.7)-
> 39.02/56 (2.5)1/45 (2.2)1/11 (9.1)-0/5 (0.0)1/51 (2.0)-
Highest temperature during hospital admission37.8 (36.4-39.8)38.1 (36.4-39.8)38.4 (37.7-39.8)0.02538.5 (37.7-39.8)38.1 (36.4-39.8)0.391
< 37.518/56 (32.1)17/45 (37.8)1/11 (9.1)0.0170/5 (0.0)16/51 (31.4)0.008
37.5-38.012/56 (21.4)11/45 (24.4)1/11 (9.1)-1/5 (20.0)11/51 (21.5)-
38.1-39.016/56 (28.6)9/45 (20.0)7/11 (63.6)-3/5 (60.0)15/51 (29.4)-
> 39.010/56 (17.8)8/45 (17.8)2/11 (18.2)-1/5 (20.0)9/51 (17.6)-
Fever duration, d7.0 (0-17)2.4 (0-17)11.0 (7-13)-10.4 (7-13)2.8 (0-17)-
Cough34/56 (60.7)29/45 (64.4)5/11 (45.4)0.3104/5 (80.0)30/51 (58.8)0.638
Sputum12/56 (21.4)6/45 (13.3)6/11 (54.5)0.0084/5 (80.0)8/51 (15.7)0.006
Breath shortness15/56 (26.7)5/45 (11.1)10/11 (90.9)0.0005/5 (100.0)10/51 (19.6)0.001
Sore throat8/56 (14.2)6/45 (13.3)2/11 (18.2)0.6491/5 (20.0)7/51 (13.7)0.552
Headache7/56 (12.5)4/45 (8.9)3/11 (27.3)0.1283/5 (60.0)4/51 (7.8)0.011
Myalgia6/56 (10.7)3/45 (6.7)3/11 (27.3)0.0833/5 (60.0)3/51 (5.9)0.007
Chest pain4/56 (7.1)2/45 (4.4)2/11 (18.2)0.1692/5 (40.0)2/51 (3.9)0.036
Fatigue10/56 (17.8)7/45 (15.5)3/11 (27.3)0.3932/5 (40.0)8/51 (15.7)0.214
Diarrhea3/56 (5.3)2/45 (4.4)1/11 (9.1)0.4881/5 (20.0)2/51 (3.9)0.249
Nausea or vomiting3/56 (5.3)2/45 (4.4)1/11 (9.1)0.4881/5 (20.0)2/51 (3.9)0.249
Throat congestion42/56 (75.0)31/45 (68.9)11/11 (100.0)0.0495/5 (100.0)37/51 (72.5)0.316
Thick lung sounds38/56 (67.8)27/45 (60.0)11/11 (100.0)0.0115/5 (100.0)33/51 (64.7)0.164
Wet and dry rales in the lungs9/56 (16.1)5/45 (11.1)4/11 (36.4)0.0635/5 (100.0)4/51 (7.8)0.000
Coexisting disorders, n (%)
Any26/56 (46.4)18/45 (40.0)8/11 (72.2)0.0095/5 (100)11/51 (21.5)0.001
Respiratory diseases2/56 (3.6)0/45 (0.0)2/11 (18.2)0.0361/5 (20.0)1/51 (2.0)0.172
Diabetes7/56 (12.5)6/45 (13.3)1/11 (9.1)1.0000/5 (0.0)7/51 (13.7)1.000
Thyroid disease (hyperthyroidism or hypothyroidism)3/56 (5.3)2/45 (4.4)1/11 (9.1)0.4881/5 (20.0)2/51 (3.9)0.249
Hypertension9/56 (16.1)9/45 (20.0)0/11 (0.0)0.1800/5 (0.0)9/51 (17.6)0.580
Cardiovascular and Cerebrovascular diseases4/56 (7.1)3/45 (6.7)1/11 (9.1)1.0001/5 (20.0)3/51 (5.9)0.320
Chronic liver diseases110/56 (17.8)9/45 (20.0)1/11 (9.1)0.6671/5 (20.0)9/51 (17.6)1.000
Nervous system disease3/56 (5.3)2/45 (4.4)1/11 (9.1)0.4881/5 (20.0)2/51 (3.9)0.249
Anal fistula1/56 (1.8)0/45 (0.0)1/11 (9.1)0.1960/5 (0.0)1/51 (2.0)1.000