Advances in para-aortic nodal dissection in gastric cancer surgery: A review of research progress over the last decade

Table 2 Some reported series of gastrectomy and a comparison of morbidity, mortality and survival between D2 and D2 + PAND

Ref.	Year	Countries and continents	Number of patients registered	Number of patients underwent D2 + PAND or D2+	Incidence of PAN (%)	Prognosis differences between D2 vs D2 + PADN (D2+)
						Morbidity			Mortality			Recurrence rate			5-yr survival rate
						D2 (%)	D2 + PAND (%)	P value	D2 (%)	D2 + PAND (%)	P value	D2 (%)	D2 + PAND (%)	P value	D2 (%)	D2 + PAND (%)	P value
Günther et al[18]	2000	Turkey	459	75	—	31.5	34.2	—	6.8	1.3	—	—	—	—	—	—	—
Bostanci et al[19]	2004	Turkey	134	34	—	10	35.3	< 0.05	1	8.8	< 0.05	—	—	—	—	—	—
Sano et al[30]	2004	Japan	523	260	—	20.9	28.1	0.067	0.8	0.8	—	—	—	—	—	—	—
Marrelli et al[17]	2007	Italy	330	79	13.9	27	27	0.929	4	4	0.82	—	—	—	—	—	—
Kunisaki et al[55]	2006	Japan	580	150	—	—	—	—	—	—	—	40	50	0.3538	56.0	50.4	0.9899
Kulig et al[20]	2007	Poland	275	134	—	27.7	21.6	0.24	4.9	2.2	0.37	—	—	—	—	—	—
Sasako et al[37]	2008	Japan	523	260	8.5	—	—	—	—	—	—	—	—	—	69.2	70.3	—
Yonemura et al[40]	2008	Japan	293	134	9.0	—	—	—	—	3.7	0.12	46.7	38.8	—	52.6	55.0	0.801
Hu et al[44]	2009	China	117	62	8.1	27.3	24.2	0.703	1.8	0	0.470	—	—	—	66.1	65.8	0.946
Roviello et al[21]	2010	Italy	286	286	12.9	—	28	—	—	2.1	—	—	—	—	—	52.2	—
Tokunaga et al[31]	2010	Japan	178	178	-	—	30	—	—	2	—	—	—	—	—	13	—
de Manzoni et al[28]	2011	Italy	294	294	16	—	—	—	—	—	—	—	—	—	—	—	—
Zhang et al[53]	2014	China	157	69	40.6	—	—	—	12.5	21.7	0.122	43.2	39.1	0.628	31.8	43.7	0.044
de Manzoni et al[78]	2015	Italy	568	294	11.6	—	—	—	4	2.4	0.340	45.3	46.3	0.866	—	—	—

PAN: Para-aortic lymph node; PAND: Para-aortic lymph node dissection.