Clinical prediction of complicated appendicitis: A case-control study utilizing logistic regression

doi:10.12998/wjcc.v8.i11.2127

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World Journal of Clinical Cases

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Control Study

World J Clin Cases. Jun 6, 2020; 8(11): 2127-2136
Published online Jun 6, 2020. doi: 10.12998/wjcc.v8.i11.2127

Table 1 Patient characteristics, n (%)

Characteristics	All (n = 236)	SA (n = 198)	CA (n = 38)	P value
Age ≥ 65 (yr)	17 (7.2)	10 (5.1)	7 (18.4)	0.001^a
Age (yr)	35.5 (25-50.5)	34 (24-45)	49 (35-63)	< 0.00^a
Male	129 (54.7)	105 (53.0)	24 (63.2)	0.251
Onset-to-visit interval (d)	1 (0-1)	1 (0-1)	1 (1-2)	< 0.001^a
Epigastric/periumbilical pain	119 (50.4)	104 (52.5)	15 (39.5)	0.141
RLQ pain	171 (72.5)	141 (71.2)	30 (79.0)	0.328
Nausea/vomiting	123 (52.1)	106 (53.5)	17 (44.7)	0.32
Diarrhea	46 (19.5)	38 (19.2)	8 (21.1)	0.791
Anorexia	64 (27.1)	48 (24.2)	16 (42.1)	0.023^a
Previous appendicitis	32 (13.6)	30 (15.2)	2 (5.3)	0.103
Diabetes mellitus	11 (4.7)	7 (3.5)	4 (10.5)	0.061
Hypertension	24 (10.2)	20 (10.1)	4 (10.5)	0.937
Dyslipidemia	21 (8.9)	16 (8.1)	5 (13.2)	0.314
Chronic lung diseases	2 (0.9)	1 (0.5)	1 (2.6)	0.19
Malignancy	1 (0.4)	1 (0.5)	0	0.661
Immunosuppressant use	1 (0.4)	1 (0.5)	0	0.661
Fever (≥ 38.0 °C)	34 (14.4)	23 (11.6)	11 (29.0)	0.005^a
Body temperature (°C)	37.0 (36.7-37.5)	37.0 (36.6-37.4)	37.5 (37.1-37.9)	< 0.001^a
Tachycardia	18 (7.6)	11 (5.6)	7 (18.4)	0.006^a
Heart rate (beats/min)	78 (68-88)	76 (66-85)	85 (76-96)	< 0.001^a
Shock	6 (2.5)	5 (2.5)	1 (2.6)	0.97
RLQ tenderness	230 (97.5)	192 (97.0)	38 (100)	0.277
Peritoneal signs	137 (58.1)	113 (57.1)	24 (63.2)	0.486
Leukocytosis	177 (75.0)	146 (73.7)	31 (81.6)	0.307
Leukocyte count (10³/mm³)	12.6 (10.1-15.2)	12.6 (10.0-15.2)	13.2 (10.8-15.4)	0.497
CRP (mg/dL)	1.1 (0.2-4.1)	0.7 (0.2-2.7)	8.8 (3.8-19.0)	< 0.001^a
GFR < 60 mL/min/1.73 m²	6 (2.5)	1 (0.5)	3 (13.2)	< 0.001^a
GFR (mL/min/1.73 m²)	120.7 (101.6-140.4)	123.8 (103.7-142.9)	105.1 (82.83-122.1)	0.007^a
Serum sodium (mEq/L)	139 (137-140)	139 (138-140)	137.5 (136-139)	0.003^a
Hyponatremia	9 (3.8)	5 (2.5)	4 (10.5)	0.019^a
ALT > 29 IU/L	38 (16.1)	30 (15.2)	8 (21.1)	0.365
Appendectomy	34 (14.4)	22 (11.1)	12 (31.6)	0.001^a

^aP < 0.05. ALT: Alanine aminotransferase; CA: Complicated appendicitis; CRP: C-reactive protein; GFR: Glomerular filtration rate; RLQ: Right lower quadrant; SA: Simple appendicitis.

Citation: Sasaki Y, Komatsu F, Kashima N, Suzuki T, Takemoto I, Kijima S, Maeda T, Miyazaki T, Honda Y, Zai H, Shimada N, Funahashi K, Urita Y. Clinical prediction of complicated appendicitis: A case-control study utilizing logistic regression. World J Clin Cases 2020; 8(11): 2127-2136
URL: https://www.wjgnet.com/2307-8960/full/v8/i11/2127.htm
DOI: https://dx.doi.org/10.12998/wjcc.v8.i11.2127