Crizotinib-induced acute fatal liver failure in an Asian ALK-positive lung adenocarcinoma patient with liver metastasis: A case report

Figure 2 Detailed changes of liver enzymes during crizotinib therapy (day 1–55) and after crizotinib discontinuation (day 56–59). A: Upper graph: aspartate aminotransferase and alanine aminotransferase; B: Lower graph: total bilirubin and prothrombin time. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; PT: Prothrombin time.