Celiac crisis, a rare occurrence in adult celiac disease: A systematic review

Table 2 Celiac disease published cases – paraclinical characteristics

Index	No	Diagnosis				Hemogram	Coagulation
		Biopsy	EMA	tTG	DGP/AGA
[26]	1	Yes, Marsh 3c	-	P, 608 U	-	Hb – L (7.8 g/dL), PLT – L	INR – H (2.1), aPTT – H (45 s)
[22]	1	Yes	P	P	P	-	-
[10]	1	Yes	-	P (> 100 U)	-	Hb – H (15.8 g/dL)	-
[27]	1	Yes, Marsh 3c	-	P (99 U/mL)	-	Hb – L (9.3 g/dL)	INR – H (3.2)
[28]	1	Yes	-	P (132 U)	-	Hb – L (4.8-12.2 g/dL)	INR – H (1.3)
[25]	1	Yes, Marsh 3c	-	P (48 U)	P/(39 U)	Hb – L (11.0 g/dL)	-
[12]	1	Yes	-	-	-	-	INR – H (3.5)
[29]	1	Yes, Marsh 4	-	P (19 UI/mL)	-	-	-
[30]	2	Yes	P (3+)	P (200 RU/mL)	-	Hb – L (8.1 g/dL), PLT – L (180000/dL)	-
		Yes	P (+1)	P (200 RU/mL)		Hb – L (7.6 g/dL), PLT – L (156000/dL)	-
[31]	1	Yes, Marsh 4	P	P (> 200 U/mL)	P	Hb – L (8.7 g/dL)	-
[32]	1	Yes	-	-	-	Hb – L	-
[33]	1	Yes	P (> 1/1280)	-	-	Hb – NR (12.3 g/dL)	-
[34]	1	Yes	P	N	-	-	-
[35]	1	Yes, Marsh 3	N	N	N	Hb – NR (12.4 g/dL), PLT – L (160000/dL)	-
[16]	12	Yes 12/12, ≥ Marsh 3a	-	P, 10/11	-	-	-
[14]	1	Yes, Marsh 3	P (92 U/mL)	-	P/(20 U/mL)	-	-
[23]	1	Yes	P (1:160)	P (15 EU/mL)	-	-	-
[36]	1	Yes, Marsh 3b	-	P (33.9 U/L)	P/(41.9 U/L)	Hb – NR, PLT – L (94000/dL)	-
[37]	1	Yes, Marsh 4	-	P (> 200 U/mL)	-	Hb – L (4.7 g/dL)	-
[38]	1	Yes, Marsh 3c	P	P	-	Hb – L (7.2 g/dL), PLT – L (257000/dL)	INR – H (> 1.5), aPTT – H (154 s)
[39]	1	Yes, Marsh 4	N	N	-	-	-
[40]	1	Yes, Marsh 3c	P (35.9 U)	P (20.6 U)	-	Hb – NR (15.2 g/dL)	INR – H (1.6)
[41]	1	Yes, Marsh 3	P (158.7)	P (> 200 U/mL)	-	Hb - L (9.4 g/dL)	-
[15]	1	Yes, Marsh 3	P	P	AGA P	Hb - L (8 g/dL)	-
[13]	1	Yes, Marsh 3c	-	P (23.4, positive > 12)	AGA P (27.4)	HT - L (18%)	PT < 10%
[42]	1	Yes, Marsh 3b	-	-	AGA P (IgA 63.4, IgG 111.1)	Hb - L	-
[8]	2	Yes, Marsh 3a; Yes, Marsh 3b	P; P	-	AGA N; AGA P	Hb - L (5.9 /dL); Hb - L (7.9 /dL)	PT prolonged (19 s); PT prolonged (18 s)
[43]	1	Yes, Marsh 3c	-	-	-	Hb - L	-
[44]	1	Yes, Marsh 3c	P (1:640)	P (142)	AGA P	Hb - L (11.6 g/dL)	INR – H (1.6)

L: Low; H: High; N: Normal; M: Masculine; Hb: Hemoglobin; P: Positive, N: Negative: NR: Normal ranges, HT: Hematocrit; AGA: Anti-gliadin antibodies; aPPT: Activated partial thromboplastin time; CD: Celiac disease; DGP: Anti-deamidated gliadin antibodies; EMA: Anti-endomysial antibodies; INR: International normalized ratio; PLT: Platelets; PT: Prothrombin time; tTG: Anti-tissue transglutaminase antibodies.