Observational Study
Copyright ©The Author(s) 2019.
World J Clin Cases. Oct 6, 2019; 7(19): 2942-2952
Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.2942
Table 1 Clinical features of patients with stiff-person syndrome
CharacteristicTotal numberClassical SPSSLS
Number of patients (n)14122
Male (%)9 (64.3)7 (58.3)2 (100)
Age of onset (yr)39.3 (28.0-54.0)35 (26.0-56.0)46.7
Follow-up duration (yr)6 (2.7-13.3)9 (2.1-14.9)4.3
Clinical feature
Low back stiffness and spasm (n)12120
Lower limb stiffness and spasm (n)14122
Lumbar lordosis (n)880
Neck stiffness and spasm (n)990
Upper limbs stiffness and spasm (n)10100
Abdominal wall stiffness and spasm (n)11110
Falls (n)1082
Exacerbating factors
Cold, noises, and emotional stress (n)14122
Excessive startle (n)981
Neurological/psychiatric feature
Seizure/epilepsy (n)220
Gait disturbances (n)12102
Parkinsonism (n)220
Alzheimer’s disease (n)220
Depression (n)541
Anxiety (n)871
Panic disorder (n)220