Expression and predictive value of miR-489 and miR-21 in melanoma metastasis

Table 7 Single-factor analysis of melanoma metastasis

Factor	Metastasis of melanoma (n = 45)	Melanoma is non-metastatic (n = 15)	t/X2	P-value
Age (yr)			6.792	0.009
≤ 50	13 (28.89)	10 (66.67)
> 50	32 (71.11)	5 (33.33)
Gender			2.222	0.136
Male	25 (55.56)	5 (33.33)
Female	20 (44.44)	10 (66.67)
Tumor size (cm)			14.470	< 0.001
≤ 2	7 (15.56)	10 (66.67)
> 2	38 (84.44)	5 (33.33)
Lesion site			0.000	1.000
Non-acral	33 (73.33)	11 (73.33)
Acral	12 (26.67)	4 (26.67)
TNM stage			35.920	< 0.001
I	0 (0.00)	7 (46.67)
II	3 (6.67)	5 (33.33)
III	22 (48.89)	3 (20.00)
IV	20 (44.44)	0 (0.00)
miR-489	0.64 ± 0.30	0.30 ± 0.16	4.179	< 0.001
miR-21	6.38 ± 2.35	4.18 ± 1.85	3.295	0.002