Multifocal G1-G2 gastric neuroendocrine tumors: Differentiating between Type I, II and III, a clinicopathologic review

Figure 1 The neuroendocrine tumors are seen as minute (less than 1-2 cm) and frequently multiple polyps. A: Gastrectomy specimen with multiple nodules/polyps, ranging in size from 0.5 mm to 2 cm; B: Gastric mucosa showing a neuroendocrine tumor (HE, 40×); C: Nested groups of cells with nuclei showing “salt and pepper” chromatin and no mitotic activity (HE, 400×); D: Ki67 proliferation index of less than 3%, consistent with a well differentiated neuroendocrine tumor G1 (Ki67 immunostain, 200×).