Biomarkers vs imaging in the early detection of hepatocellular carcinoma and prognosis

doi:10.12998/wjcc.v7.i12.1367

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Jun 26, 2019; 7(12): 1367-1382
Published online Jun 26, 2019. doi: 10.12998/wjcc.v7.i12.1367

Table 2 International guidelines for hepatocellular carcinoma diagnosis

Guideline	Liver nodule US	Biomarkers	Indications for biomarkers
Canadian	CT/MRI/CEUS	AFP, AFP-L3, DCP	Late stage/aggressive
AASLD	CT/MRI
ACG	CT/MRI
NCCN	CT/MRI
Australian	CT/MRI/CEUS: Selected case
EASL	CT/MRI/CEUS
ESMO	CT/MRI
Japan	CT/MRI	AFP, AFP-L3, DCP	Definitive diagnosis, efficacy of treatment
Asia-Pacific	CT/MRI/CEUS

AFP: Alpha-fetoprotein; AFP-L3: Alpha-fetoprotein L3; AASLD: American Association for the Study of Liver Diseases; CEUS: Contrast-enhanced computed tomography; CT: Computed tomography; DCP: Des-gamma-carboxyprothrombin; EASL: European Association for the Study of the Liver; ESMO: European Society for Medical Oncology; MRI: Magnetic resonance imaging; NCCN: National Comprehensive Cancer Network; US: Ultrasonography.

Citation: Balaceanu LA. Biomarkers vs imaging in the early detection of hepatocellular carcinoma and prognosis. World J Clin Cases 2019; 7(12): 1367-1382
URL: https://www.wjgnet.com/2307-8960/full/v7/i12/1367.htm
DOI: https://dx.doi.org/10.12998/wjcc.v7.i12.1367