Genetic associations of inflammatory bowel disease in a South Asian population

Table 2 Results of the case’s control analysis for the association of single nucleotide polymorphisms with inflammatory bowel disease

SNPs	Variant allele	Genotypes	Controls (465), n (%)	Cases (415), n (%)	Odds ratio1	95%CI		P
rs10045431	C	AA	5 (1.08)	5 (1.2)
		CA	114 (24.52)	83 (20)	0.77	0.56	1.06	0.11
		CC	346 (74.41)	327 (78.8)	1.06	0.30	3.69	0.93
rs11805303	T	CC	93 (20)	53 (12.77)
		TC	236 (50.75)	207 (49.88)	1.54	1.05	2.26	0.03
		TT	136 (29.25)	155 (37.35)	2.00	1.33	3.01	0.00
rs12612347	G	AA	67 (14.41)	69 (16.63)
		GA	229 (49.25)	191 (46.02)	0.81	0.55	1.19	0.29
		GG	169 (36.34)	155 (37.35)	0.89	0.60	1.33	0.57
rs13361189	C	TT	267 (57.42)	235 (56.63)
		CT	172 (36.99)	153 (36.87)	1.01	0.76	1.34	0.94
		CC	26 (5.59)	27 (6.51)	1.18	0.67	2.08	0.57
rs1558744	A	GG	347 (74.62)	289 (69.64)
		AG	116 (24.95)	118 (28.43)	1.22	0.90	1.65	0.19
		AA	2 (0.43)	8 (1.93)	4.80	1.01	22.79	0.04
rs1728785	A	CC	261 (56.13)	253 (60.96)
		CA	184 (39.57)	139 (33.49)	0.78	0.59	1.03	0.08
		AA	20 (4.3)	23 (5.54)	1.19	0.64	2.21	0.59
rs3024505	A	GG	373 (80.22)	322 (77.59)
		GA	89 (19.14)	89 (21.45)	1.16	0.83	1.61	0.38
		AA	3 (0.65)	4 (0.96)	1.54	0.34	6.95	0.57
rs3737240	T	CC	262 (56.34)	215 (51.81)
		TC	172 (36.99)	167 (40.24)	1.18	0.90	1.56	0.24
		TT	31 (6.67)	33 (7.95)	1.30	0.77	2.19	0.33
rs4613763	C	TT	461 (99.14)	408 (98.31)	1.98	0.57	6.80	0.28
		CT	4 (0.86)	7 (1.69)	0.89	0.77	1.01	0.07
		CC	0 (0)	0 (0)
rs5771069	A	GG	264 (56.77)	248 (59.76)
		GA	160 (34.41)	144 (34.7)	0.96	0.72	1.27	0.77
		AA	41 (8.82)	23 (5.54)	0.60	0.35	1.02	0.06
rs6017342	A	CC	217 (46.67)	223 (53.73)
		CA	200 (43.01)	154 (37.11)	0.75	0.57	0.99	0.04
		AA	48 (10.32)	38 (9.16)	0.77	0.48	1.23	0.27
rs744166	G	AA	86 (18.49)	100 (24.1)
		AG	238 (51.18)	203 (48.92)	0.73	0.52	1.03	0.08
		GG	141 (30.32)	112 (26.99)	0.68	0.47	1.00	0.05
rs7809799	G	AA	405 (87.1)	361 (86.99)
		GA	58 (12.47)	50 (12.05)	0.97	0.65	1.45	0.87
		GG	2 (0.43)	4 (0.96)	2.24	0.41	12.32	0.35
rs886774	G	AA	154 (33.12)	104 (25.06)
		GA	214 (46.02)	199 (47.95)	1.38	1.01	1.89	0.05
		GG	97 (20.86)	112 (26.99)	1.71	1.18	2.47	0.00
rs9268853	C	TT	210 (45.16)	203 (48.92)
		CT	208 (44.73)	164 (39.52)	0.82	0.62	1.08	0.16
		CC	47 (10.11)	48 (11.57)	1.06	0.68	1.65	0.81
rs9822268	A	GG	284 (61.08)	280 (67.47)
		GA	163 (35.05)	117 (28.19)	0.73	0.55	0.97	0.03
		AA	18 (3.87)	18 (4.34)	1.01	0.52	1.99	0.97

¹Reports the odds of being a case for heterozygous and homozygous individuals with the recessive allele compared to the controls. SNPs: Single nucleotide polymorphisms.