Leukocyte function-associated antigen-1 deficiency impairs responses to polymicrobial sepsis

Figure 11 Neutrophil recruitment to the lung. A: Leukocyte recruitment to the alveolar space was examined by BAL. The number of leukocytes in BAL was shown. Statistical analysis was performed using two-tailed Student’s t test. There was no statistical significance (P = 0.1158); B and C: Neutrophil recruitment to the lung was examined by measuring myeloperoxidase level. In the figure, control means no cecal ligation and puncture surgery, and CLP means cecal ligation and puncture model. Data represent mean ± SD of 4 different samples. Statistical analysis was performed using one-way analysis of variance with Tukey post hoc analysis. ^aP < 0.05. Isotype means isotype control antibody. M17/4 is anti-CD11a blocking antibody. KO: Knockout; CLP: Cecal ligation and puncture; MPO: Myeloperoxidase; WT: Wild type.