Cardiovascular risk factors for acute stroke: Risk profiles in the different subtypes of ischemic stroke

Table 4 Results of multivariate analysis: cardiovascular risk factors independently associated with the different subtypes of ischemic infarction in 2704 consecutive patients with cerebral infarction collected from the “Sagrat Cor Hospital of Barcelona Stroke Registry”[7]

	Odds ratio (95%CI)
Atherothrombotic infarction
Peripheral vascular disease	2.28 (1.68-3.08)
Hypertension	1.84 (1.53-2.2)
Diabetes mellitus	1.66 (1.36-2.03)
Previous transient ischemic attack	1.50 (1.16-1.95)
Chronic obstructive pulmonary disease	1.41 (1.04-1.93)
Previous cerebral infarction	1.40 (1.12-1.76)
Ischemic heart disease	1.33 (1.06-1.68)
Atrial fibrillation	0.36 (0.28-0.45)
Heart valve disease	0.23 (0.12-0.43)
Lacunar infarction
Hypertension	2.64 (2.19-3.20)
Diabetes mellitus	1.55 (1.23-1.90)
Obesity (≥ 30 kg/m2)	1.50 (1.01-2.25)
Oral anticoagulation	0.37 (0.16-0.82)
Heart valve disease	0.22 (0.17-0.28)
Cardioembolic
Atrial fibrillation	20.01 (15.98-25.05)
Heart valve disease	5.60 (3.60-8.71)
Ischemic heart disease	2.09 (1.57-2.78)
Dyslipidemia	0.69 (0.50-0.94)
Diabetes mellitus	0.68 (0.52-0.89)
Hypertension	0.67 (0.54-0.85)
Previous transient ischemic attack	0.66 (0.46-0.95)
Smoking (> 20 cigarettes/d)	0.54 (0.34-0.88)
Obesity (≥ 30 kg/m2)	0.38 (0.20-0.73)
Undetermined cause
Hypertension	0.12 (0.09-0.17)
Peripheral vascular disease	0.13 (0.04-0.41)
Atrial fibrillation	0.15 (0.10-0.23)
Diabetes mellitus	0.21 (0.13-0.32)
Ischemic heart disease	0.24 (0.13-0.42)
Heart valve disease	0.34 (0.14-0.80)
Previous cerebral infarction	0.61 (0.40-0.93)
Unusual cause
Atrial fibrillation	0.15 (0.07-0.32)
Diabetes mellitus	0.17 (0.07-0.38)
Ischemic heart disease	0.21 (0.08-0.58)
Hypertension	0.27 (0.18-0.42)