Castleman disease variant of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes syndrome: A case report

doi:10.12998/wjcc.v14.i8.118789

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World Journal of Clinical Cases

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2307-8960

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Case Report

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Cases. Mar 16, 2026; 14(8): 118789
Published online Mar 16, 2026. doi: 10.12998/wjcc.v14.i8.118789

Table 1 Sensory nerve conduction study

Sensory NCS
Nerve/sites	Rec. site	Latency, ms	Amplitude, µV	Segments	Distance, cm	Vel., m/s
Left median - digit II (antidromic)
Wrist	Index	5.31¹	2.7¹	Wrist - index	14	34.9
Right median - digit II (antidromic)
Wrist	Index	5.42¹	5.6¹	Wrist - index	15	35.1
Left ulnar - digit V (antidromic)
Wrist	Dig V	4.64¹	4.4¹	Wrist - dig V	12	33.9
Right ulnar - digit v (antidromic)
Wrist	Dig V	5.10¹	4.0¹	Wrist - dig V	12	31.6
Left radial - superficial (antidromic)
Forearm	Wrist	NR¹	NR¹	Forearm - wrist	10	NR
Right radial - superficial (antidromic)
Forearm	Wrist	NR¹	NR¹	Forearm - wrist	10	NR
Left sural - (antidromic)
Calf	Ankle	NR¹	NR¹	Calf - ankle	14	NR
Right sural - (antidromic)
Calf	Ankle	NR¹	NR¹	Calf - ankle	14	NR

¹Abnormal results; normal ranges are based on the local population and adjusted for the patient’s height (1.69 m).

NR: No response; NCS: Nerve conduction study; Dig: Digit.

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Citation: Paw LJ, Tan JK, Teoh CX, Megat Mohamad Aminuddin PNA, Agusalim AF, Cheong XK, Payus AO, Wan Nik Ahmad Mustafa WAK, Omar UA, Mustafa N, Chong GY, Tumian NR, Abdul Wahid SF, Chong CY, Tan HJ, Remli R. Castleman disease variant of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes syndrome: A case report. World J Clin Cases 2026; 14(8): 118789
URL: https://www.wjgnet.com/2307-8960/full/v14/i8/118789.htm
DOI: https://dx.doi.org/10.12998/wjcc.v14.i8.118789

Paw LJ, Tan JK, Teoh CX, Megat Mohamad Aminuddin PNA, Agusalim AF, Cheong XK, Payus AO, Wan Nik Ahmad Mustafa WAK, Omar UA, Mustafa N, Chong GY, Tumian NR, Abdul Wahid SF, Chong CY, Tan HJ, Remli R. Castleman disease variant of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes syndrome: A case report. World J Clin Cases 2026; 14(8): 118789 [DOI: 10.12998/wjcc.v14.i8.118789]

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