Esophageal stricture due to amyloidosis in plasma cell dyscrasia: A case report and review of literature

Figure 4 Bone marrow findings demonstrating an underlying plasma-cell dyscrasia. A: Bone marrow aspirate smear showing increased mature and immature plasma cells with eccentrically placed nuclei, abundant basophilic cytoplasm, and perinuclear hof (black circle); residual erythroid and myeloid precursors are also present (Giemsa ×200); B: Immunohistochemical staining shows plasma cells with membranous CD138 expression (x100); C: The neoplastic plasma cells demonstrated positive expression for lambda light-chain (×100); D: Negative for kappa light chain, indicating lambda light chain restriction (×100) .