Esophageal stricture due to amyloidosis in plasma cell dyscrasia: A case report and review of literature

doi:10.12998/wjcc.127546

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Cases. Oct 26, 2026; 14(28): 127546
Published online Oct 26, 2026. doi: 10.12998/wjcc.127546

Table 2 Workup for plasma cell dyscrasia

Parameters	Patient value	Reference range
M-Spike	2.27 g/dL (27.8%) (present)	Present/absent
Serum free kappa light chain (mg/L)	16.14	3.3-19.4
Serum free lambda light chain (mg/L)	752.40	5.7-26.3
Free κ/λ ratio	0.02	0.26-1.65
Urine Bence Jones protein	Negative	Negative
Spot protein creatinine ratio	100	< 150 mg/g
Whole body PET-CT	Diffuse circumferential esophageal wall thickening (up to 7 mm) without significant FDG uptake, no hypermetabolic lesions seen elsewhere

FDG: ¹⁸F-fluorodeoxyglucose; PET-CT: Positron emission tomography-computed tomography.

Full Size Table

Citation: Sachdeva S, Sirohi N, Mandal K, Bansal D, Vaithiyam V, Dalal A, Goyal S, Sakhuja P. Esophageal stricture due to amyloidosis in plasma cell dyscrasia: A case report and review of literature. World J Clin Cases 2026; 14(28): 127546
URL: https://www.wjgnet.com/2307-8960/full/v14/i28/127546.htm
DOI: https://dx.doi.org/10.12998/wjcc.127546

Sachdeva S, Sirohi N, Mandal K, Bansal D, Vaithiyam V, Dalal A, Goyal S, Sakhuja P. Esophageal stricture due to amyloidosis in plasma cell dyscrasia: A case report and review of literature. World J Clin Cases 2026; 14(28): 127546 [DOI: 10.12998/wjcc.127546]

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