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Case Report
Copyright: ©Author(s) 2026.
World J Clin Cases. Oct 26, 2026; 14(28): 125577
Published online Oct 26, 2026. doi: 10.12998/wjcc.125577
Table 1 Local factors relevant to peripheral giant cell granuloma
Category
Examples
Clinical relevance
Biofilm-related factorsPlaque, calculus, food impactionSustain chronic gingival inflammation
Prosthetic/restorative factorsOverhanging margins, poor marginal adaptation, rough surfaces, defective pontic design, poor emergence profileIncrease plaque retention and/or soft tissue trauma
Periodontal factorsChronic periodontitis, deep inflammation around abutment teethMay contribute to a reactive gingival environment
Traumatic factorsRepetitive mechanical irritation, impinging prosthetic componentsPromote persistent local injury
Systemic/contextual contributorsHormonal changes, xerostomia, impaired hygiene accessMay increase susceptibility, though usually not sufficient alone


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