Aprepitant as add-on to standard antiemetic regimen for concurrent chemoradiotherapy induced nausea vomiting in head and neck cancer

doi:10.12998/wjcc.122960

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Cases. Aug 16, 2026; 14(23): 122960
Published online Aug 16, 2026. doi: 10.12998/wjcc.122960

Table 4 Degree (intensity) of nausea during acute and delayed-phases in both the groups as per MASSC Antiemesis Tool Scale, mean ± SD

Phase of emesis	Group A	Group B	P value
Acute- phase	0.65 ± 1.85	2.49 ± 3.37	0.004
Delayed-phase
Day 2	0.76 ± 1.97	1.90 ± 3.00	0.05
Day 3	0.53 ± 1.77	2.30 ± 3.09	0.002
Day 4	0.54 ± 1.75	2.18 ± 3.11	0.004
Day 5	0.90 ± 2.30	1.53 ± 2.74	0.210

Data analysed by the Mann Whitney U test.

Full Size Table

Citation: Gupta N, Sehgal S, Mittal N. Aprepitant as add-on to standard antiemetic regimen for concurrent chemoradiotherapy induced nausea vomiting in head and neck cancer. World J Clin Cases 2026; 14(23): 122960
URL: https://www.wjgnet.com/2307-8960/full/v14/i23/122960.htm
DOI: https://dx.doi.org/10.12998/wjcc.122960