Copyright: ©Author(s) 2026.
World J Clin Cases. Aug 6, 2026; 14(22): 121062
Published online Aug 6, 2026. doi: 10.12998/wjcc.121062
Published online Aug 6, 2026. doi: 10.12998/wjcc.121062
Table 3 Certainty (grading of recommendations assessment, development, and evaluation) of evidence of the outcomes
| Outcome | Number of studies | Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other consideration | Certainty of evidence |
| IBS and CRC | 6 | 6 cross-sectional | Not serious | Serious (I2 = 79%) | Not serious | Serious | None | Very low |
| IBS and CRC | 3 | Three retrospective | Not serious | Serious (I2 = 99%) | Not serious | Serious | None | Very low |
| IBS and CRC, removing outliers | 5 | Four cross-sectional and 1 cohort | Not serious | Not serious (I2 = 0%) | Not serious | Not serious | None | Low |
- Citation: Mirghani HO, Alanazi GO. Irritable bowel syndrome and colon cancer: A meta-analysis. World J Clin Cases 2026; 14(22): 121062
- URL: https://www.wjgnet.com/2307-8960/full/v14/i22/121062.htm
- DOI: https://dx.doi.org/10.12998/wjcc.121062