Systematic review of multidisciplinary team strategies and novel research in rare and complex clinical cases

Table 1 Electronic database search strategy

Database	Search terms	Limits applied
PubMed	(“Patient Care Team”[Mesh] OR “Interdisciplinary Communication”[Mesh] OR “Delivery of Health Care, Integrated”[Mesh] OR “Clinical Decision-Making”[Mesh] OR multidisciplinary[tiab] OR “multidisciplinary team”[tiab] OR MDT[tiab] OR interdisciplinary[tiab] OR interprofessional[tiab] OR “team-based care”[tiab] OR “integrated care”[tiab] OR “collaborative care”[tiab] OR “tumor board”[tiab] OR “tumour board”[tiab] OR “molecular tumor board”[tiab] OR “case conference”[tiab] OR “expert panel”[tiab] OR “precision medicine board”[tiab] OR “genomic board”[tiab]) AND (“Rare Diseases”[Mesh] OR “Neoplasms”[Mesh] OR “Cardiovascular Diseases”[Mesh] OR “Nervous System Diseases”[Mesh] OR “Congenital Abnormalities”[Mesh] OR “Autoimmune Diseases”[Mesh] OR rare disease*[tiab] OR complex condition*[tiab] OR oncology[tiab] OR cancer*[tiab] OR cardiology[tiab] OR neurology[tiab] OR congenital[tiab] OR autoimmune[tiab]) AND (“Precision Medicine”[Mesh] OR “Artificial Intelligence”[Mesh] OR “Genomics”[Mesh] OR “High-Throughput Nucleotide Sequencing”[Mesh] OR “Decision Support Systems, Clinical”[Mesh] OR precision medicine[tiab] OR genomic*[tiab] OR AI[tiab] OR “artificial intelligence”[tiab] OR “machine learning”[tiab] OR “clinical decision support”[tiab])	Humans; English; 2013-2025
Cochrane Library	(Multidisciplinary OR interdisciplinary OR interprofessional OR “team-based care” OR “integrated care” OR “collaborative care” OR “tumor board” OR “tumour board” OR “case conference” OR “expert panel”) AND (rare OR complex OR oncology OR cancer OR cardiology OR neurology OR congenital OR autoimmune)	2013-2025

MDT: Multidisciplinary team.