Bipolar disorder with multiple comorbidities of a 55-year-old female patient: A case report

doi:10.12998/wjcc.v14.i10.118579

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Cases. Apr 6, 2026; 14(10): 118579
Published online Apr 6, 2026. doi: 10.12998/wjcc.v14.i10.118579

Table 1 Treatment protocol

Drug class	Medication	Dosage regimen	Rationale
Mood stabilizer	Sodium valproate	500 mg → 1500 mg/day	Primary choice for mixed episodes; avoids thyroid interactions
Atypical antipsychotic	Quetiapine	100 mg → 600 mg/day	Guideline-recommended (CANMAT) for mixed features; favorable metabolic profile vs. Olanzapine
Comorbidity management	Felodipine	5 mg/day	BP < 140/90 mmHg

Dosage titration was performed based on clinical response and tolerability. CANMAT: Canadian Network for Mood and Anxiety Treatments.

Full Size Table

Citation: Li HL. Bipolar disorder with multiple comorbidities of a 55-year-old female patient: A case report. World J Clin Cases 2026; 14(10): 118579
URL: https://www.wjgnet.com/2307-8960/full/v14/i10/118579.htm
DOI: https://dx.doi.org/10.12998/wjcc.v14.i10.118579

Li HL. Bipolar disorder with multiple comorbidities of a 55-year-old female patient: A case report. World J Clin Cases 2026; 14(10): 118579 [DOI: 10.12998/wjcc.v14.i10.118579]

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