Early pleuroparenchymal fibroelastosis mimicking lung malignancy: A case report

Figure 2 Gross and histopathology of the resected left upper lobe consistent with pleuroparenchymal fibroelastosis. A: Gross specimen with diffuse visceral pleural thickening and a firm gray to black subpleural lesion (white circle) corresponding to the radiological abnormality, scale: Centimeter ruler provided; B: Hematoxylin and eosin staining (× 40 magnification) showed dense fibroelastic thickening of the visceral pleura extending into the adjacent subpleural lung parenchyma with minimal inflammation and no malignant features, inset: Elastic Van Gieson staining (× 100 magnification) highlighted abundant elastic fiber deposition within the pleura and subpleural alveolar septa, consistent with pleuroparenchymal fibroelastosis (scale bar: 600 μm). L: Lung parenchyma; P: Pleura.