©The Author(s) 2025.
World J Clin Cases. Nov 6, 2025; 13(31): 109113
Published online Nov 6, 2025. doi: 10.12998/wjcc.v13.i31.109113
Published online Nov 6, 2025. doi: 10.12998/wjcc.v13.i31.109113
Table 3 Summary of symptoms reported, n (%)
| Adverse event | Placebo (n = 40) | Physta® 50 mg (n = 36) | Physta® 100 mg (n = 36) | Total (n = 112) | Severity | Outcome | Related to product |
| Bloating | 2 (5.0) | 3 (8.3) | 4 (11.1) | 9 (8.0) | Mild | Resolved | No |
| Headache | 1 (2.5) | 2 (5.6) | 2 (5.6) | 5 (4.5) | Mild | Resolved | No |
| Breast tenderness | 0 (0.0) | 1 (2.8) | 2 (5.6) | 3 (2.7) | Mild | Resolved | No |
| Flatulence | 1 (2.5) | 2 (5.6) | 2 (5.6) | 5 (4.5) | Mild | Resolved | No |
| Abdominal discomfort | 1 (2.5) | 1 (2.8) | 2 (5.6) | 4 (3.6) | Mild | Resolved | No |
| Total events | 5 (12.5) | 9 (25.0) | 12 (33.3) | 26 (23.2) | - | - | - |
- Citation: Muniandy S, Yahya HM, Shahar S, Kamisan Atan I, Mahdy ZA, Rajab NF, Mohd Rasdi HF, George A, Chinnappan SM. Effect of Eurycoma longifolia water extract (Physta®) on menopausal quality of life and mood states. World J Clin Cases 2025; 13(31): 109113
- URL: https://www.wjgnet.com/2307-8960/full/v13/i31/109113.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v13.i31.109113