Splenic histiocytic sarcoma: Disease progression from the perspective of pathophysiology

Figure 3 Changes in liver function from the first admission to the last admission of the case. A: Total protein (TP), albumin, and globulin concentrations. The black arrows in the figure denote the infusion of frozen plasma and 20% human albumin. The range between the dotted lines represents the normal reference range for a given index (TP: Dot; albumin: Short line; globulin: Dot and short line alternate); B: Total bilirubin (TBIL), direct bilirubin (DBIL), and indirect bilirubin (IBIL) concentrations. The black arrow in the figure denotes hepatoprotective drug therapy. The range between the dotted lines represents the normal reference range for a given index (TBIL: Dot; IBIL: Short line; DBIL: Dot and short line alternate). The gray arrows in the figure represent surgical treatment. Phases 1, 2, and 3, delineated by the solid black line, correspond to early SHS, mid-SHS, and late SHS, respectively. TP: Total protein; TBIL: Total bilirubin; DBIL: Direct bilirubin; IBIL: Indirect bilirubin.