Diagnostic accuracy of circulating miR-146, miR-221 and miR-222 in papillary thyroid cancer: A systematic review and meta-analysis

Table 3 Quality assessment of the included studies

Ref.	Risk of bias				Applicability concerns
	Patient selection	Index test	Reference standard	Flow and timing	Patient selection	Index test	Reference standard
Lee et al[26]	Low risk	Unclear risk	Low risk	Low risk	Low risk	Unclear risk	Low risk
Zhang et al[24]	High risk	Unclear risk	Low risk	Low risk	High risk	Unclear risk	Low risk
Zhang et al[27]	High risk	Unclear risk	Low risk	Low risk	High risk	Unclear risk	Low risk
Rosignolo et al[23]	Low risk	Unclear risk	Low risk	Low risk	Low risk	Unclear risk	Low risk
Jiang et al[25]	Low risk	Unclear risk	Low risk	Low risk	Low risk	Unclear risk	Low risk
Yu et al[22]	Low risk	Unclear risk	Low risk	Low risk	Low risk	Unclear risk	Low risk