Hepatitis B virus and hepatitis D virus co-infection complicated by autoimmune hepatitis: Two case reports

doi:10.12998/wjcc.v13.i26.104421

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Sep 16, 2025 (publication date) through Aug 4, 2025

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Sep 16, 2025; 13(26): 104421
Published online Sep 16, 2025. doi: 10.12998/wjcc.v13.i26.104421

Table 2 Laboratory and pathological results related to autoimmune hepatitis

Test/feature		Case 1	Case 2
Anti-nuclear antibody		1:320	1:320
IgG (g/L) elevation		47.10	22.60
Liver kidney microsomal type 1 antibody		-	+
Anti-soluble liver antigen antibody		-	-
Pathology	Portal inflammation	Moderate	Moderate
	Interface hepatitis	Mild to moderate	Moderate
	Plasma cell infiltration	Present	Present
	Rosette formation	Absent	Absent
	Piecemeal necrosis	Absent	Absent
Inflammation grade (G)		G3	G2
Fibrosis stage (S)		S4	S3

IgG: Immunoglobulin G.

Citation: Dou J, Zhao XY, Wang ZG, Ning ZH, Wang XZ, Guo F. Hepatitis B virus and hepatitis D virus co-infection complicated by autoimmune hepatitis: Two case reports. World J Clin Cases 2025; 13(26): 104421
URL: https://www.wjgnet.com/2307-8960/full/v13/i26/104421.htm
DOI: https://dx.doi.org/10.12998/wjcc.v13.i26.104421