Hepatitis B virus and hepatitis D virus co-infection complicated by autoimmune hepatitis: Two case reports

Table 1 Laboratory tests, cirrhosis status and treatment for case 1

Test item	August 2023	November 2023
Current antiviral medication	Tenofovir propofol fumarate	Tenofovir propofol fumarate
Cirrhosis stage	Decompensated	Decompensated
ALT (U/L)	985.00	17.20
AST (U/L)	2115.0	23.50
GGT (U/L)	161.61	28.93
ALP(U/L)	198.83	57.50
Alb (g/L)	27.38	41.10
TBIL (μmol/L)	97.20	45.90
DBIL (μmol/L)	60.22	23.60
IBIL(μmol/L)	36.98	22.30
LDH (U/L)	653.11	267.88
CHE (U/L)	2240	1310.00
TBA (μmol/L)	126.40	176.20
TP (g/L)	80.56	61.80
Glb (g/L)	53.18	20.70
PT (seconds)	26.80	22.20
PTA (%)	27.70	40.50
INR	2.29	1.73
WBC (109/L)	1.55	1.57
HGB (g/L)	105.00	73.00
PLT (109/L)	103.00	60.00
IgG (g/L)	47.10	13.62
AFP (ng/mL)	16.80	3.84
HBsAg (IU/mL)	12286.00	14214.00
HBeAg (IU/mL)	0.12	0.13
HBV DNA (IU/mL)	1.12 × 102	< 20
Anti-HDV IgM	Positive	Positive
Anti-HDV IgG	Positive	Positive
Liver stiffness (kPa)	16.5	17.6
Fat attenuation (db/m)	268	246
Non-alcoholic fatty liver disease	Present	Present

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transferase; ALP: Alkaline phosphatase; Alb: Albumin; TBIL: Total bilirubin; DBIL: Direct bilirubin; IBIL: Indirect bilirubin; LDH: Lactate dehydrogenase; CHE: Cholinesterase; TBA: Total bile acid; TP: Total protein; Glb: Globulin; PT: Prothrombin time; PTA: Prothrombin time activity; INR: International normalized ratio; WBC: White blood cell; HGB: Hemoglobin; PLT: Platelet; IgG: Immunoglobulin G; AFP: Alpha-fetoprotein; HBsAg: Hepatitis B surface antigen; HBeAg: Hepatitis B e antigen; HBV: Hepatitis B virus; HDV: Hepatitis D virus; IgM: Immunoglobulin M.