Effects of herbal medicines containing Paeoniae Radix on patients with restless legs syndrome: A retrospective chart review study

doi:10.12998/wjcc.v13.i25.108244

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Sep 6, 2025; 13(25): 108244
Published online Sep 6, 2025. doi: 10.12998/wjcc.v13.i25.108244

Table 4 Comparisons of the Korean version of the International Restless Legs Scale scores according to the herbal medicine containing Paeoniae Radix type

HCP	Administration group
HCP	Baseline	After treatment	P value
Gyejibokryeonghwan (n = 7)	26.0 ± 9.7	10.0 ± 9.4	0.028¹
Jakyakgamchotang (n = 5)	23.2 ± 12.6	6.6 ± 4.2	0.042¹
Sihogyejitang (n = 3)	30.0 ± 7.0	23.0 ± 13.5	0.414
Dangguijakyaksan (n = 4)	27.3 ± 8.8	19.8 ± 18.0	0.273
Danggwisayeokgaohsuyusaenggangtang (n = 2)	19.0 ± 5.7	21.5 ± 3.5	0.180
Gamisoyosan (n = 3)	23.3 ± 10.2	16.0 ± 4.4	0.109

¹Statistically significant at P < 0.05 by Wilcoxon signed-rank test. mean ± SD values are displayed. The Wilcoxon signed-rank test was employed for comparing the values before and after treatment. HCP: Herbal medicine containing Paeoniae Radix.

Citation: Lee YS, Lee HG, Kwon S, Cho SY, Jung WS, Park SU, Moon SK, Park JM, Ko CN. Effects of herbal medicines containing Paeoniae Radix on patients with restless legs syndrome: A retrospective chart review study. World J Clin Cases 2025; 13(25): 108244
URL: https://www.wjgnet.com/2307-8960/full/v13/i25/108244.htm
DOI: https://dx.doi.org/10.12998/wjcc.v13.i25.108244