Tramadol overdose in total knee arthroplasty: A case report

doi:10.12998/wjcc.v13.i25.104742

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Sep 6, 2025 (publication date) through Jul 28, 2025

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

World J Clin Cases. Sep 6, 2025; 13(25): 104742
Published online Sep 6, 2025. doi: 10.12998/wjcc.v13.i25.104742

Table 1 Test results and parameters

Test	Result
Blood urea	72 mg/dL
Serum creatinine	3.8 mg/dL
eGFR	36 mL/minute/1.73 m²
HbA1c	7.2
CBC, LFT, coagulation, echo, doppler	Within normal limits
Urinalysis (protein, sugar)	Normal
Vital signs	BP: 122/68 mmHg, HR: 72 bpm, RR: 15, SpO₂: 92%
ABG	pH: 7.25 (mild respiratory acidosis)
CT & MRI brain	Cortical atrophy, lacunar infarcts
CT pulmonary angiography	No embolism or pneumonitis
Echocardiogram	Normal
Doppler (lower limbs)	No DVT
Tramadol level	1.8 mg/L (elevated; normal: 0.1-0.8 mg/L)

eGFR: Estimated glomerular filtration rate; HbA1c: Glycated hemoglobin; CBC: Complete blood count; LFT: Liver function tests; BP: Blood pressure; HR: Heart rate; RR: Respiratory rate; SpO₂: Oxygen saturation; ABG: Arterial blood gas; CT: Computer tomography; MRI: Magnetic resonance imaging; DVT: Deep vein thrombosis.

Citation: Harna B, Arya S. Tramadol overdose in total knee arthroplasty: A case report. World J Clin Cases 2025; 13(25): 104742
URL: https://www.wjgnet.com/2307-8960/full/v13/i25/104742.htm
DOI: https://dx.doi.org/10.12998/wjcc.v13.i25.104742