Diagnostic performance of 99mTc-PSMA SPECT/CT in primary prostate carcinoma

Figure 3 A 65-year-old man presented with difficult and painful micturition, S. PSA 932 ng/dL, and G-III prostatomegaly on USG. A and B: ^99mTc-PSMA planar images show increased heterogenous tracer uptake in the prostate gland region (orange arrow), pelvic nodes (green arrow), and thorax (blue arrow; likely lung and mediastinal nodes); C and D: Axial CT and SPECT-CT fused images show increased tracer uptake in the enlarged prostate gland involving the seminal vesicles, the urinary bladder wall, and the rectum with few pelvic nodes; E and F: Focal increased tracer uptake in the sacrum without corresponding CT lesion (yellow arrow; likely metastatic). Biopsy from the prostate was positive for malignancy.