Off-label use of treprostinil in adult patients in clinical cases

Table 2 World Health Classification of pulmonary hypertension and treprostinil indications

Group	Indication	Treprostinil use status
Group 1	Pulmonary arterial hypertension	Approved
Group 2	Pulmonary hypertension due to left heart disease	Has not been tested
Group 3	Pulmonary hypertension associated with lung disorders	Off-label use
Group 4	Pulmonary hypertension due to pulmonary artery obstructions	Off-label use
Group 5	Miscellaneous (unclear or multifactorial mechanisms)	Has not been tested