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©The Author(s) 2025.
World J Clin Cases. Aug 16, 2025; 13(23): 107279
Published online Aug 16, 2025. doi: 10.12998/wjcc.v13.i23.107279
Published online Aug 16, 2025. doi: 10.12998/wjcc.v13.i23.107279
Table 1 Treprostinil mechanisms of action
| Number | Effect |
| 1 | Vasodilation |
| 2 | Inhibition of platelets aggregation |
| 3 | Inhibition of platelets adherence |
| 4 | Reversion of pulmonary remodelling |
| 5 | Decrease of muscle cell proliferation rate |
| 6 | Regulation of vascular homeostasis |
| 7 | Attenuation of inflammatory response |
| 8 | Upregulation of apoptosis rate |
| 9 | Elevation of ATP production |
| 10 | Preservation of mitochondrial biogenesis |
- Citation: Mouratidou C, Pavlidis ET, Katsanos G, Kotoulas SC, Tsoulfas G, Mouloudi E, Taitzoglou IA, Galanis IN, Pavlidis TE. Off-label use of treprostinil in adult patients in clinical cases. World J Clin Cases 2025; 13(23): 107279
- URL: https://www.wjgnet.com/2307-8960/full/v13/i23/107279.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v13.i23.107279