Mediastinal lymphadenopathy: Causes, symptoms and factors predicting good yield of endoscopic ultrasound-guided biopsy

Table 7 Factors predicting good yield of endoscopic ultrasound guided biopsy of enlarged mediastinal lymph nodes (n = 243)

Clinical variable		Univariate analysis					Multivariate analysis
		Good yield	Poor yield	Odds Ratio	Confidence interval	P value
Age	< 40	68	11	0.57	0.249–1.337	0.195
	> 40	150	14
Gender	Male	115	16	0.63	0.266–1.482	0.285
	Female	103	9
Location of node	Subcarinal	180	16	2.66	1.096–6.478	0.026
	Others	38	9
Size of LN	≥ 12 mm	200	13	10.25	4.083–25.762	< 0.0001	0.005
	< 12 mm	18	12
Bore of the needle used	22G	211	25	0.89	0.856–0.934	1.000
	25G	7	0
Type of needle	FNB	202	20	3.16	1.046–9.523	0.049
	FNA	16	5
Number of passes	≥ 2	201	21	2.25	0.693–7.317	0.247
	< 2	17	4
MOSE	Satisfactory	202	9	22.44	8.574–58.753	< 0.0001	< 0.0001
	Unsatisfactory	16	16

FNA: Fine needle aspiration; FNB: Fine needle biopsy; LN: Lymph node; MOSE: Macroscopic on-site evaluation.