©The Author(s) 2025.
World J Clin Cases. Aug 6, 2025; 13(22): 105596
Published online Aug 6, 2025. doi: 10.12998/wjcc.v13.i22.105596
Published online Aug 6, 2025. doi: 10.12998/wjcc.v13.i22.105596
Table 4 Causes of mediastinal lymphadenopathy found on endoscopic ultrasound guided biopsy (n = 243)
| Causes of mediastinal lymphadenopathy | n (%) |
| Tuberculosis | 82 (33.7%) |
| Anthracosis | 53 (21.8) |
| Minimal to mild | 32 |
| Moderate | 14 |
| Severe | 7 |
| Neoplastic disease | 43 (17.7) |
| Metastatic | |
| Breast cancer | 9 |
| Lung cancer | 7 |
| Pancreatobiliary cancer | 6 |
| Esophageal cancer | 5 |
| Renal cancer | 5 |
| Hepatocellular cancer | 2 |
| Neuroendocrine cancer | 2 |
| Gastrointestinal stromal tumor | 1 |
| Undetermined origin | 3 |
| Primary | |
| Lymphoproliferative disorder | 2 |
| Kaposi’s sarcoma | 1 |
| Sarcoidosis | 14 (5.8) |
| Miscellaneous | 12 (4.9) |
| Epithelioid cell collection | 5 |
| Post chemotherapy changes | 2 |
| Necrotic tissue | 2 |
| Keratin slough | 2 |
| Granulomatous inflammation | 1 |
| Normal histology | 23 (9.5) |
| Suboptimal tissue | 16 (6.6) |
- Citation: Tasneem AA, Luck NH, Mubarak M. Mediastinal lymphadenopathy: Causes, symptoms and factors predicting good yield of endoscopic ultrasound-guided biopsy. World J Clin Cases 2025; 13(22): 105596
- URL: https://www.wjgnet.com/2307-8960/full/v13/i22/105596.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v13.i22.105596