Value of glucose transport protein 1 expression in detecting lymph node metastasis in patients with colorectal cancer

Table 1 Correlation between glucose transport protein 1 expression and clinicopathological parameters

	GLUT-1 (center)		P value	GLUT-1 (periphery)		P value
	(-) (n = 83)	(+) (n = 86)		(-) (n = 78)	(+) (n = 91)
Age (yr ± SD)	64.0 ± 11.4	64.7 ± 12.6	0.740	64.0 ± 11.6	64.7 ± 12.4	0.718
Sex
Male	52	54	0.985	51	55	0.507
Female	31	32		27	36
Tumor size (mean ± SD)	4.9 ± 1.8	5.2 ± 2.0	0.277	5.1 ± 1.7	5.1 ± 2.1	0.932
T stage
T1, 2	16	7	0.035	11	12	0.836
T3, 4	67	79		67	79
N stage
N0	51	48	0.457	48	51	0.47
N1-2	32	38		30	40
AJCC stage
I, II	49	48	0.672	47	50	0.486
III, IV	34	38		31	41
Lymphatic invasion
Negative	70	72	0.913	64	78	0.517
Positive	13	14		14	13
Perineural invasion
Negative	66	73	0.361	68	71	0.12
Positive	17	13		10	20
Blood glucose level (mean ± SD)	110.5 ± 36.2	111.6 ± 25.8	0.818	112.4 ± 38.8	109.9 ± 23.2	0.612
SUVmax of primary tumor (mean ± SD)	12.3 ± 5.9	16.1 ± 7.4	<0.001	13.0 ± 6.4	15.3 ± 7.3	0.030
SUVmax of lymph node (mean ± SD)	1.04 ± 2.6	2.15 ± 3.1	0.012	0.99 ± 2.6	2.13 ± 3.0	0.010

GLUT-1: Glucose transport protein 1; SD: Standard deviation; AJCC: American Joint Committee on Cancer; SUV: Standardized uptake value.