Inverse relationship between platelet Akt activity and hippocampal atrophy: A pilot case-control study in patients with diabetes mellitus

Table 3 Voxel-based specific regional analysis for Alzheimer’s Disease Z-scores and the medication (exogenous insulin, glucagon-like peptide-1 receptor agonist or metformin) of the diabetes mellitus subjects

Patient	Z-score	Patient	Z-score	Patient	Z-score	Patient	Z-score
1	1.33	11	0.25	212	0.94	31	1.95
2	0.38	12	0.82	223	0.39	32	0.71
3	1.01	13	0.67	231,3	0.65	33	1.65
41	0.34	14	0.38	24	0.59	34	0.63
51	0.35	15	0.41	25	1.14	35	0.72
6	0.68	16	0.31	26	0.67	36	1.65
7	0.51	17	0.54	27	1.18	37	1.49
8	1.04	181	1.93	28	0.72	38	0.79
9	0.23	19	1.62	29	0.58	39	0.87
10	0.49	20	1.05	30	0.95	40	1.06

¹Exogenous insulin-medicated.

²Glucagon-like peptide-1 receptor agonist-medicated.

³Metformin-medicated.

Voxel-based specific regional analysis system for AD (VSRAD) registered the target volume of interest (VOI) in the medial temporal lobe including hippocampus. The individual Z-scores in the target VOI (VSRAD Z-score) are presented.