Congophilic fibrils in the glomeruli with polyclonal immunoglobulin gamma staining - another cause for diagnostic overlap: A case report

Figure 2 Mass spectrometry protein identification report (“scaffold”) shows presence of proteins deposited with amyloid of all types including serum amyloid P component, apolipoprotein A4 and apolipoprotein E; thereby confirming the diagnosis of amyloidosis. In addition, it also shows high peptide counts for IgG heavy chain and lambda light chain, but kappa light chains are seen as well.