Clinicopathological features and expression of regulatory mechanism of the Wnt signaling pathway in colorectal sessile serrated adenomas/polyps with different syndrome types

Table 2 Protein expression of β-catenin, adenomatous polyposis coli, and mutated in colorectal cancer in patients with large intestine damp-heat (Da-Chang-Shi-Re) syndrome and spleen-stomach weakness (Pi-Wei-Xu-Ruo) syndrome

	DCSR syndrome, n = 30	PWXR syndrome, n = 30	P value
β-catenin	0.32 ± 0.03	0.20 ± 0.02	P < 0.0001
APC	0.17 ± 0.01	0.23 ± 0.02	P < 0.0001
MCC	0.18 ± 0.01	0.24 ± 0.01	P < 0.0001

APC: Adenomatous polyposis coli; DCSR: Large intestine damp-heat (Da-Chang-Shi-Re); MCC: Mutated in colorectal cancer; PWXR: Spleen-stomach weakness (Pi-Wei-Xu-Ruo).