Collagen matrix scaffolds: Future perspectives for the management of chronic liver diseases

Figure 2 Collagen matrix scaffold implantation in hepatocellular carcinoma. Collagen matrix scaffold (CMS) can be used alone or in combination with hepatocellular carcinoma cell lines (e.g., HEP-G2 and/or HuH7) as a 3D model. Resection of tumor- or liver-damaged tissue and subsequent implantation of CMS alone or impregnated with antineoplastic drugs can be used to evaluate drug bioavailability and improve liver function.